MmpL Proteins in Physiology and Pathogenesis of M. tuberculosis
Mycobacterium tuberculosis (Mtb) remains an important human pathogen.The Mtb cell envelope is a critical bacterial structure that contributes to virulence and pathogenicity.Mycobacterial membrane protein large (MmpL) proteins export bulky, hydrophobic substrates that are essential for the unique Rainbow Brite structure of the cell envelope and dire